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The JWH molecules were being 1st synthesized by John William Huffman at Clemson University within the late 1990s.[eighty three] The FBI concluded inside a 2012 memo that because of the publication of J.W. Huffman's research, individuals looking for a "marijuana-like-high" would follow his recipes and techniques.[five] PB-22 and 5F-PB-22 were being